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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB2
All Species:
5.76
Human Site:
T458
Identified Species:
9.05
UniProt:
Q9UBS0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBS0
NP_003943.2
482
53483
T458
L
P
P
P
P
P
S
T
T
A
P
L
P
I
R
Chimpanzee
Pan troglodytes
XP_001172909
482
53404
T458
L
P
P
P
P
P
S
T
T
A
P
L
P
I
R
Rhesus Macaque
Macaca mulatta
XP_001117937
512
56562
P485
L
P
P
P
P
P
L
P
P
S
I
T
A
P
L
Dog
Lupus familis
XP_851971
482
53401
P456
L
P
P
P
P
P
P
P
S
S
T
A
P
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M4
485
53520
P458
L
P
S
P
P
S
P
P
P
T
S
T
A
P
L
Rat
Rattus norvegicus
P67999
525
59113
E482
P
M
E
T
S
G
I
E
Q
M
D
V
T
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
E439
P
M
E
T
S
G
I
E
Q
M
D
V
T
T
S
Chicken
Gallus gallus
P18652
752
84421
S469
A
V
K
V
I
D
K
S
K
R
D
P
S
E
E
Frog
Xenopus laevis
P10665
733
82620
K451
V
K
V
I
D
K
T
K
R
D
P
S
E
E
I
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
K455
V
K
I
I
D
K
S
K
R
D
P
S
E
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
R1089
R
I
P
K
R
T
H
R
V
V
R
T
L
P
P
Honey Bee
Apis mellifera
XP_395876
456
51514
H433
H
F
H
L
H
N
N
H
V
Q
N
H
R
H
N
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
T493
K
K
A
V
F
D
A
T
E
E
V
D
I
L
L
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
Q463
P
S
S
A
R
P
I
Q
P
I
E
E
A
M
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
K447
S
S
P
N
S
D
A
K
A
N
P
F
T
N
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
91.8
95
N.A.
92.9
65.7
N.A.
70.9
30
30.5
30.2
N.A.
21.1
56.8
29.9
60.9
Protein Similarity:
100
99.7
92.5
96.6
N.A.
95
76
N.A.
80.9
42.8
42.5
43.2
N.A.
28.3
70.7
43.1
74.5
P-Site Identity:
100
100
40
46.6
N.A.
26.6
0
N.A.
0
0
6.6
13.3
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
100
46.6
66.6
N.A.
26.6
6.6
N.A.
6.6
6.6
20
20
N.A.
6.6
6.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
0
0
14
0
7
14
0
7
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
14
20
0
0
0
14
20
7
0
0
7
% D
% Glu:
0
0
14
0
0
0
0
14
7
7
7
7
14
20
7
% E
% Phe:
0
7
0
0
7
0
0
0
0
0
0
7
0
0
7
% F
% Gly:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% G
% His:
7
0
7
0
7
0
7
7
0
0
0
7
0
7
0
% H
% Ile:
0
7
7
14
7
0
20
0
0
7
7
0
7
14
14
% I
% Lys:
7
20
7
7
0
14
7
20
7
0
0
0
0
0
0
% K
% Leu:
34
0
0
7
0
0
7
0
0
0
0
14
7
14
20
% L
% Met:
0
14
0
0
0
0
0
0
0
14
0
0
0
7
0
% M
% Asn:
0
0
0
7
0
7
7
0
0
7
7
0
0
7
7
% N
% Pro:
20
34
40
34
34
34
14
20
20
0
34
7
20
20
14
% P
% Gln:
0
0
0
0
0
0
0
7
14
7
0
0
0
0
0
% Q
% Arg:
7
0
0
0
14
0
0
7
14
7
7
0
7
0
14
% R
% Ser:
7
14
14
0
20
7
20
7
7
14
7
14
7
0
14
% S
% Thr:
0
0
0
14
0
7
7
20
14
7
7
20
20
14
0
% T
% Val:
14
7
7
14
0
0
0
0
14
7
7
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _